BALTIMORE -- As poorly as they played for the first seven innings, it seemed hard to imagine the Baltimore Orioles would be celebrating an uplifting victory well after midnight. Nick Mullens Super Bowl Jersey . Then again, strange things happen when the Chicago White Sox are involved. Nelson Cruz hit a game-tying grand slam in the eighth inning and David Lough scored the winning run on a wild pitch in the 12th to give the Orioles a 5-4 victory Wednesday night. Nick Markakis had four hits for the Orioles, who won two of three from Chicago -- twice in their last at-bat. "Its big," Lough said. "Thats our second walk-off win against these guys. Theyre a good team. Give credit to them and their pitching staff for holding us." The Orioles didnt get a runner past first base against White Sox starter Hector Noesi until the seventh inning and trailed 4-0 entering the eighth. Noesi was pulled after giving up two straight singles, and Scott Downs walked Chris Davis to load the bases with two outs. Chicago manager Robin Ventura summoned Javy Guerra, the fourth pitcher of the inning, to face Cruz. On a 2-1 pitch, Cruz launched an opposite-field drive that barely cleared the wall in right field. It was his 24th home run, the second grand slam of the season and eighth of his career. "I had the chance to do some damage in a couple of at-bats before then, but I grounded into a double play twice," Cruz said. "It feels good to get the home run to tie the game." Said Lough: "Thats a big-time clutch hit right there, as big as it gets. Thats who we want at the plate, because he leads this team. You see what hes capable of doing and the numbers hes put up. Hes a special player." Neither team threatened before the grounds crew came with the tarp as soon as the ninth inning ended. Rain delayed the start of the 10th for 69 minutes. Nick Hundley opened the bottom of the 12th with a walk off Daniel Webb (4-2) and Lough entered as a pinch-runner. Lough took third on a single by Markakis and scored easily when Webb uncorked a pitch that got past catcher Tyler Flowers. "Its tough to lose like that," Ventura said. "Hector threw a great game, but we couldnt hold onto it. Weve got to be able to be better at the end." Tommy Hunter (2-1) got the final out in the Chicago 12th to earn the win. "It didnt look like it was a 4-4 game or it ended up being 5-4 in the first seven innings," Orioles manager Buck Showalter said. "Eight innings. Whatever it was. It seems like yesterday. It was yesterday." Jose Abreu hit his 23rd home run for the White Sox, Adam Eaton tied a career high with four hits and Flowers drove in two runs. Abreu has four homers and 10 RBIs during his current 10-game hitting streak. None of it mattered. "The way we played, we should have (won), but the baseball gods must be upset with us in some way, shape, or form," Eaton said. Baltimore starter Ubaldo Jimenez allowed four runs and eight hits in 6 1-3 innings. The right-hander left the mound in danger of absorbing his ninth loss, but Cruzs slam took Jimenez off the hook. Until Cruz connected, Noesi and the White Sox dominated. Abreu provided Chicago a 1-0 lead by hitting the first pitch of the fourth inning into the seats in left. In the fifth, Alejandro De Aza drew a leadoff walk and scored on a triple by Eaton. The Orioles pulled the infield in, and that resulted in Eaton being thrown out at the plate on a grounder to third. Flowers hit a two-run single in the seventh to make it 4-0. That seemingly provided a bit of breathing room for the White Sox, whose previous seven games were decided by two runs or fewer. Unfortunately for Chicago, the lead didnt hold up. "That was my fault, I put this game on myself," Guerra said. "I have to be better in that situation, no matter what. I need to understand the situation. I feel bad for the team in general because I know I let everyone down." NOTES: Baltimore is off Thursday. Chicago sends Scott Carroll to the mound in the opener of a four-game series against host Toronto. ... Orioles RHP Bud Norris (strained groin) was supposed to pitch in Fridays split doubleheader against Tampa Bay. Chris Tillman will start instead, and Norris might not pitch again until Tuesday. He was expected to have an MRI on Thursday, Showalter said. ... Eaton has reached base in 20 straight games and owns a career-best 12-game hitting streak. Mitch Wishnowsky Super Bowl Jersey . Rico dove horizontally to meet Andoni Iraolas precise long cross from the right to score his second league goal of the season in the 33rd minute. Two minutes later, Aritz Aduriz netted Bilbaos second when he raced forward and pounced on a poor clearance by Villarreal defender Mateo Musacchio, sending a low shot rolling past goalkeeper Sergio Asenjo. Jaquiski Tartt Super Bowl Jersey .com) - Delon Wright made all 12 of his free throws and finished with 21 points and six assists as No.(SportsNetwork.com) - The Florida Panthers will attempt to get their playoff chances back on track Saturday evening as they visit the New Jersey Devils. The Panthers halted a season-high five-game skid with Thursdays 3-2 win over the Columbus Blue Jackets. It also brought a 10-game skid versus Columbus to an end as well as a six-game losing streak at home. Sean Bergenheim played slump-buster by potting the game-winning goal with 6:52 left to play. He deflected a wrister from Dmitry Kulikov into the net right before taking a stick to the face by the Blue Jackets Jack Johnson. Lucky I got the puck first, then I took the stick on the mouth, Bergenheim said. Jonathan Huberdeau and rookie Aaron Ekblad both scored in the second period for the Panthers, who got 30 saves from Roberto Luongo. Aleksander Barkov, coming off a three-point game, had an assist to give him 10 points in his past 10 contests. Floridas recent skid has put it six points behind the New York Rangers for the Eastern Conferences second wild card spot. The Panthers hope to rebound tonight, but the Devils have won four of the past five encounters oveerall. Jason Verrett Super Bowl Jersey. That includes a 5-1 victory in Florida back on Oct. 11. New Jersey has won four in a row at home in this series. Luongo is 10-14-0 in his career versus the Devils, posting a 2.93 goals against average, .912 save percentage and three shutouts in 24 meetings. The Devils were aiming for a third victory in a row last night in a matchup with the visiting Pittsburgh Penguins, but collapsed late in a 2-1 overtime setback. Peter Harrold took a late high-sticking penalty in the third period and the Pens cashed in to tie the game with 3:11 on the clock before Simon Despres won it with 2:39 remaining in overtime. He used a screen to beat Devils netminder Cory Schneider. No penalty at that time is a good penalty. It gave them life. Couldnt afford to do that, said Harrold. Steve Bernier scored in the loss and Schneider made a season-high 41 saves in his league-leading 43rd start. Keith Kinkaid is expected to start in net tonight and has never before faced the Panthers. Kinkaid is 1-3-3 on the season in nine games (5 starts) with a 2.54 goals against average and .913 save percentage. ' ' '